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Author Contributions All authors contributed to data analysis, drafting or revising the article, have agreed on the journal to which the article will be submitted, gave final approval of the version to be published, and agree to be accountable for all aspects of the work

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Smaller proteins can enter the pores, have a more convoluted path and, thus, take longer to traverse the matrix and elute from the column

Table 1 Effects of bacterial virulence factors on Wnt/-catenin signaling pathway